Table 1.

IC₅₀ of Toxel, VCR, ADR, BLM in CD147 transfectants (MT3), shCD147 transfectants (AT3) and their negative controls

Drugs	MCF7	Vehicle vector	MT3	MCF7/Adr	Vehicle vector	AT3
Toxel	0.0140 ± 0.0210	0.0187 ± 0.0050	*0.7562 ± 0.0238	0.4018 ± 0.1322	0.3857 ± 0.0966	*0.0698 ± 0.0025
VCR	0.4658 ± 0.0946	0.5021 ± 0.0359	*9.2321 ± 0.3561	13.7932 ± 0.4546	12.9825 ± 0.4879	*2.3164 ± 0.1598
ADR	0.4126 ± 0.1201	0.5980 ± 0.0200	*43.1548 ± 3.0068	30.0355 ± 6.2413	28.6307 ± 6.4592	*8.8400 ± 0.1014
BLM	0.5386 ± 0.0231	0.6013 ± 0.0021	0.5932 ± 0.1026	0.4769 ± 0.0863	0.5567 ± 0.0987	0.5031 ± 0.1372

ADR, adriamycin; BLM, bleomycin; Toxel, paclitoxel; VCR, vincristine. IC₅₀ values are expressed in µM and were evaluated as reported in Materials and Methods. Standard deviations for all of the experiments carried outin triplicate were less than 5%. *P < 0.05 vs control cells.