Table 3.
Sensitivity, specificity, PPV and NPV stratified by PSA, TAM count and MSR count at the first biopsy
Parameter | Benign | Cancer | Sensitivity/Specificity | PPV*/NPV |
---|---|---|---|---|
High PSA (≥8.8) | 27 | 21 | 21/30 | 21/48 |
Low PSA (<8.8) | 35 | 9 | 35/62 | 35/44 |
High TAM count (≥16) | 25 | 14 | 14/30 | 14/39 |
Low TAM count (<16) | 37 | 16 | 37/62 | 37/53 |
Low MSR count (<32) | 18 | 25 | 44/62 | 44/49 |
High MSR count (≥32) | 44 | 5 | 25/30 | 25/43 |
PSA, prostate‐specific antigen; TAM, tumor‐associated macrophage; MSR, macrophage scavenger receptor; *PPV, positive predictive value; NPV, negative predictive value.