Table 2.
Localization | Tissue code | PDGF‐AB* | PDGF‐BB* | VEGF‐A* | VEGF‐D* | GM‐CSF* | G‐CSF* | bFGF* | HGF* | MVD |
---|---|---|---|---|---|---|---|---|---|---|
CUP | 1 | 99 | 23 | 1102 | 0 | 16 | 21 | 703 | 3469 | 10 |
CUP | 2 | 0 | 6.5 | 514 | 8.4 | 2.5 | 0 | 544 | 1959 | 38 |
CUP | 3 | 0 | 8.7 | 16 | 6 | 0.9 | 0 | 335 | 710 | 37 |
CUP | 4 | 0 | 0 | 0 | 0 | 5.9 | 0 | 544 | 1084 | 18 |
CUP | 5 | 0 | 22.5 | 3930 | 0 | 9.5 | 0 | 375 | 3046 | n.a. |
CUP | 6 | 36.5 | 17.5 | 340 | 0 | 3.5 | 11 | 261 | 542 | 72 |
CUP | 7 | 35 | 12.5 | 1606 | 0 | 0 | 0 | 1516 | 1692 | 36 |
CUP | 8 | 18 | 12.5 | 72.5 | 0 | 0 | 0 | 310 | 1747 | 41 |
CUP | 9 | 13.5 | 10.5 | 74 | 0 | 8 | 8 | 424 | 1516 | 25 |
CUP | 10 | 34 | 15 | 1738 | 0 | 3 | 45 | 1710 | 1920 | 14 |
CUP | 11 | 34 | 0 | 160 | 0 | 0 | 0 | 541 | 3600 | 18 |
Oropharynx | 12 | 232 | 98 | 280 | 20 | 10 | 35 | 975 | 3785 | n.a. |
Oropharynx | 13 | 0 | 12.7 | 2 | n.a. | 3 | 0 | 244 | n.a. | 45 |
Oropharynx | 14 | 37 | 32 | 140 | 0 | 31 | 99 | 1182 | 2603 | 9 |
Oropharynx | 15 | 57.5 | 64 | 956 | 0 | 13.5 | 0 | 243 | 1795 | 60 |
Oropharynx | 16 | 31 | 14.5 | 42 | 0 | 0 | 14 | 2024 | 3132 | 126 |
Oropharynx | 17 | 18.5 | 10.5 | 218 | 0 | 0 | 0 | 626 | 1515 | n.a. |
Oropharynx | 18 | 0 | 0 | 177 | 0 | 1 | 0 | 277 | 2224 | 7 |
Oropharynx | 19 | 71.5 | 30 | 100 | 0 | 0 | 33 | 1007 | 4421 | 62 |
Oropharynx | 20 | 0 | 0 | 311 | 0 | 0 | 0 | 1233 | 1354 | 18 |
Oropharynx | 21 | 36 | 10.5 | 36 | 0 | 0 | 0 | 1224 | 890 | 120 |
Larynx | 22 | 19 | 16 | 57 | 0 | 0 | 15 | 1854 | 3927 | 13 |
Larynx | 23 | 60 | 61 | 530 | 0 | 177.5 | 213 | 1027 | 2099 | 14 |
Larynx | 24 | 0 | 43 | 143 | 0 | 6 | 30 | 1519 | 6188 | 11 |
Larynx | 25 | 0 | 0 | 105 | 0 | 0 | 0 | 747 | 1805 | 28 |
Larynx | 26 | 0 | 52 | 369 | 0 | 0 | 0 | 1701 | 2504 | 21 |
Larynx | 27 | 17.5 | 9.5 | 332 | 0 | 0 | 35 | 566 | 2938 | 42 |
Larynx | 28 | 64 | 48.5 | 93 | 0 | 40.5 | 116 | 1021 | 1843 | 25 |
Larynx | 29 | 27 | 13.5 | 114 | 0 | 9.5 | 327 | 2184 | 1537 | 24 |
Larynx | 30 | 49 | 17.5 | 264 | 0 | 0 | 0 | 642 | 1793 | 29 |
Larynx | 31 | 0 | 0 | 66 | 0 | 6 | 164 | 2574 | 7108 | 28 |
Hypopharynx | 32 | 0 | 0 | 67 | 0 | 4 | 0 | 457 | 1417 | 14 |
Hypopharynx | 33 | 22.5 | 0 | 60 | 0 | 3.5 | 23 | 1902 | 3468 | 13 |
Hypopharynx | 34 | 24.5 | 0 | 464 | 0 | 10 | 52 | 1760 | 962 | 30 |
Hypopharynx | 35 | 52 | 0 | 3877 | 0 | 0 | 0 | 1814 | 3186 | n.a. |
Hypopharynx | 36 | 30 | 30 | 789 | 0 | 0 | 0 | 959 | 6476 | 20 |
Hypopharynx | 37 | 57 | 0 | 3088 | 0 | 0 | 0 | 1201 | 4654 | 58 |
Hypopharynx | 38 | 17.5 | 12 | 127 | 0 | 4 | 41 | 2954 | 6235 | 25 |
Hypopharynx | 39 | 14 | 0 | 169 | 0 | 39 | 621 | 2046 | 6459 | 87 |
Hypopharynx | 40 | 23.5 | 14.5 | 479 | 0 | 0 | 15 | 885 | 5322 | 62 |
Hypopharynx | 41 | 0 | 0 | 140 | 0 | 0 | 36 | 1160 | 1688 | 50 |
Mean | 30 | 17.3 | 564.6 | 0.9 | 9.9 | 47.7 | 1104.2 | 2865.3 | 36.5 |
Concentrations of angiogenic growth factors (pg/mg total protein); n.a., not assessed; MVD, microvessel density, mean number of microvessels per field; PDGF‐AB, platelet derived growth factor AB; PDGF‐BB, platelet derived growth factor BB; VEGF‐A, vascular endothelial growth factor A; VEGF‐D, vascular endothelial growth factor D; GM‐CSF, granulocyte macrophage colony‐stimulating factor; G‐CSF,granulocyte colony‐stimulating factor; bFGF, basic fibroblast growth factor; HGF, hepatocyte growth factor.