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. 2009 Mar 12;100(7):1210–1218. doi: 10.1111/j.1349-7006.2009.01158.x

Table 2.

Quantitative growth factors levels in head and neck squamous cell carcinoma (HNSCC) tissues

Localization Tissue code PDGF‐AB* PDGF‐BB* VEGF‐A* VEGF‐D* GM‐CSF* G‐CSF* bFGF* HGF* MVD
CUP  1  99 23 1102  0  16  21  703 3469  10
CUP  2   0  6.5  514  8.4   2.5   0  544 1959  38
CUP  3   0  8.7   16  6   0.9   0  335  710  37
CUP  4   0  0    0  0   5.9   0  544 1084  18
CUP  5   0 22.5 3930  0   9.5   0  375 3046 n.a.
CUP  6  36.5 17.5  340  0   3.5  11  261  542  72
CUP  7  35 12.5 1606  0   0   0 1516 1692  36
CUP  8  18 12.5   72.5  0   0   0  310 1747  41
CUP  9  13.5 10.5   74  0   8   8  424 1516  25
CUP 10  34 15 1738  0   3  45 1710 1920  14
CUP 11  34  0  160  0   0   0  541 3600  18
Oropharynx 12 232 98  280 20  10  35  975 3785 n.a.
Oropharynx 13   0 12.7    2 n.a.   3   0  244 n.a.  45
Oropharynx 14  37 32  140  0  31  99 1182 2603   9
Oropharynx 15  57.5 64  956  0  13.5   0  243 1795  60
Oropharynx 16  31 14.5   42  0   0  14 2024 3132 126
Oropharynx 17  18.5 10.5  218  0   0   0  626 1515 n.a.
Oropharynx 18   0  0  177  0   1   0  277 2224   7
Oropharynx 19  71.5 30  100  0   0  33 1007 4421  62
Oropharynx 20   0  0  311  0   0   0 1233 1354  18
Oropharynx 21  36 10.5   36  0   0   0 1224  890 120
Larynx 22  19 16   57  0   0  15 1854 3927  13
Larynx 23  60 61  530  0 177.5 213 1027 2099  14
Larynx 24   0 43  143  0   6  30 1519 6188  11
Larynx 25   0  0  105  0   0   0  747 1805  28
Larynx 26   0 52  369  0   0   0 1701 2504  21
Larynx 27  17.5  9.5  332  0   0  35  566 2938  42
Larynx 28  64 48.5   93  0  40.5 116 1021 1843  25
Larynx 29  27 13.5  114  0   9.5 327 2184 1537  24
Larynx 30  49 17.5  264  0   0   0  642 1793  29
Larynx 31   0  0   66  0   6 164 2574 7108  28
Hypopharynx 32   0  0   67  0   4   0  457 1417  14
Hypopharynx 33  22.5  0   60  0   3.5  23 1902 3468  13
Hypopharynx 34  24.5  0  464  0  10  52 1760  962  30
Hypopharynx 35  52  0 3877  0   0   0 1814 3186 n.a.
Hypopharynx 36  30 30  789  0   0   0  959 6476  20
Hypopharynx 37  57  0 3088  0   0   0 1201 4654  58
Hypopharynx 38  17.5 12  127  0   4  41 2954 6235  25
Hypopharynx 39  14  0  169  0  39 621 2046 6459  87
Hypopharynx 40  23.5 14.5  479  0   0  15  885 5322  62
Hypopharynx 41   0  0  140  0   0  36 1160 1688  50
Mean  30 17.3  564.6  0.9   9.9  47.7 1104.2 2865.3  36.5
*

Concentrations of angiogenic growth factors (pg/mg total protein); n.a., not assessed; MVD, microvessel density, mean number of microvessels per field; PDGF‐AB, platelet derived growth factor AB; PDGF‐BB, platelet derived growth factor BB; VEGF‐A, vascular endothelial growth factor A; VEGF‐D, vascular endothelial growth factor D; GM‐CSF, granulocyte macrophage colony‐stimulating factor; G‐CSF,granulocyte colony‐stimulating factor; bFGF, basic fibroblast growth factor; HGF, hepatocyte growth factor.