Table 4.
Genes highly expressed in high lymph node metastasis group (incidence > 80%) after orthotopic implantation of colorectal cancer cells onto the cecal walls of mice using Matrigel
| NCBI Acc. No. | OGS | Name | t‐value | P‐value |
|---|---|---|---|---|
| NM_017831.2 | RNF125 | Ring finger protein 125 | –5.97 | 9.34E‐05 |
| INCYTE UNIQUE | null | Null | –5.51 | 1.83E‐04 |
| NM_017976.1 | GABPB2 | GA binding protein transcription factor, beta subunit 2 | –4.92 | 4.56E‐04 |
| NM_001080496.1 | KIAA0258 | KIAA0258 | –4.82 | 5.36E‐04 |
| AF190164.1 | PRELP | Proline/arginine‐rich end leucine‐rich repeat protein | –4.80 | 5.53E‐04 |
| NM_153758.1 | IL19 | Interleukin 19 | –4.73 | 6.22E‐04 |
| NM_016535.3 | ZNF581 | Zinc finger protein 581 | –4.72 | 6.33E‐04 |
| AF132599.1 | KLF13 | Kruppel‐like factor 13 | –4.69 | 6.62E‐04 |
| NM_014972.1 | TCF25 | Transcription factor 25 (basic helix‐loop‐helix) | –4.61 | 7.58E‐04 |
| U90918.1 | NPAL3 | NIPA‐like domain containing 3 | –4.51 | 8.82E‐04 |
| AK092741.1 | CRIP1 | Cysteine‐rich protein 1 (intestinal) | –4.48 | 9.25E‐04 |
| NM_024594.2 | PANK3 | Pantothenate kinase 3 | –4.46 | 9.55E‐04 |
| N28878.1 | TMED5 | Transmembrane emp24 protein transport domain containing 5 | –4.36 | 1.14E‐03 |
| NM_001001973.1 | ATP5C1 | ATP synthase, H + transporting, mitochondrial F1 complex, gamma polypeptide 1 | –4.34 | 1.17E‐03 |
| AW665284.1 | DIAPH3 | Diaphanous homolog 3 (Drosophila) | –4.24 | 1.38E‐03 |
| NM_001398.2 | ECH1 | Enoyl Coenzyme A hydratase 1, peroxisomal | –4.12 | 1.71E‐03 |
| NM_024578.1 | OCEL1 | Occludin/ELL domain containing 1 | –4.01 | 2.05E‐03 |
| NM_139015.3 | UNQ1887 | Signal peptide peptidase 3 | –3.97 | 2.18E‐03 |
| NM_004176.3 | SREBF1 | Sterol regulatory element binding transcription factor 1 | –3.92 | 2.38E‐03 |
| NM_032376.2 | RASA4 | RAS p21 protein activator 4 | –3.83 | 2.81E‐03 |
| NM_014918.3 | CHSY1 | Carbohydrate (chondroitin) synthase 1 | –3.82 | 2.83E‐03 |
| NM_019021.1 | C11orf71 | Chromosome 11 open reading frame 71 | –3.81 | 2.87E‐03 |
| XM_042698.8 | USP22 | Ubiquitin‐specific peptidase 22 | –3.71 | 3.43E‐03 |
| NM_001706.2 | BCL6 | B‐cell CLL/lymphoma 6 (zinc finger protein 51) | –3.71 | 3.47E‐03 |
| NM_005198.3 | CHKB | Choline kinase beta | –3.67 | 3.66E‐03 |
| NM_001677.3 | ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | –3.65 | 3.80E‐03 |
| NM_017747.1 | ANKHD1 | Ankyrin repeat and KH domain containing 1 | –3.63 | 3.92E‐03 |
| NM_003826.1 | NAPG | N‐ethylmaleimide‐sensitive factor attachment protein, gamma | –3.63 | 3.97E‐03 |
| NM_032528.1 | ST6GAL2 | ST6 beta‐galactosamide alpha‐2,6‐sialyltranferase 2 | –3.54 | 4.60E‐03 |
| NM_002202.2 | ISL1 | ISL1 transcription factor, LIM/homeodomain (islet‐1) | –3.50 | 4.97E‐03 |
t‐values and P‐values were indicated with an individual two‐sample t‐test. E‐05, E‐04 and E‐03 represent 10−5, 10−4 and 10−3, respectively. NCBI Acc. No., National Center for Biotechnology Information accession number; OGS, official gene symbol.