Table 5.
Genes expressed at a low rate in high lymph node metastasis group (incidence > 80%) after orthotopic implantation of colorectal cancer cells onto the cecal walls of mice using Matrigel
| NCBI Acc. No. | OGS | Name | t‐value | P‐value |
|---|---|---|---|---|
| NM_032024.2 | C10orf11 | Chromosome 10 open reading frame 11 | 6.06 | 8.14E‐05 |
| NM_003898.2 | SYNJ2 | Synaptojanin 2 | 5.77 | 1.25E‐04 |
| NM_007375.3 | TARDBP | TAR DNA binding protein | 5.65 | 1.50E‐04 |
| NM_015481.1 | ZNF385 | Zinc finger protein 385 | 5.61 | 1.58E‐04 |
| NM_032603.2 | LOXL3 | Lysyl oxidase‐like 3 | 5.03 | 3.84E‐04 |
| NM_139344.1 | BIN1 | Bridging integrator 1 | 4.41 | 1.05E‐03 |
| NM_001427.2 | EN2 | Engrailed homolog 2 | 4.38 | 1.09E‐03 |
| NM_199160.1 | LHX6 | LIM homeobox 6 | 4.38 | 1.10E‐03 |
| NM_175080.1 | P2RX5 | Purinergic receptor P2X, ligand‐gated ion channel, 5 | 4.33 | 1.19E‐03 |
| NM_030758.2 | OSBP2 | Oxysterol binding protein 2 | 4.27 | 1.31E‐03 |
| NM_016429.1 | COPZ2 | Coatomer protein complex, subunit zeta 2 | 4.23 | 1.40E‐03 |
| NM_003670.1 | BHLHB2 | Basic helix–loop–helix domain containing, class B, 2 | 4.22 | 1.43E‐03 |
| NM_014381.1 | MLH3 | MutL homolog 3 | 4.15 | 1.62E‐03 |
| NM_002355.2 | M6PR | Mannose‐6‐phosphate receptor (cation dependent) | 4.07 | 1.85E‐03 |
| NM_003304.4 | TRPC1 | Transient receptor potential cation channel, subfamily C, member 1 | 4.07 | 1.86E‐03 |
| NM_018647.2 | TNFRSF19 | Tumor necrosis factor receptor superfamily, member 19 | 3.97 | 2.19E‐03 |
| NM_006000.1 | TUBA4A | Tubulin, alpha 4a | 3.97 | 2.20E‐03 |
| NM_001979.4 | EPHX2 | Epoxide hydrolase 2, cytoplasmic | 3.91 | 2.42E‐03 |
| NM_001755.2 | CBFB | Core‐binding factor, beta subunit | 3.91 | 2.44E‐03 |
| NM_001044385.1 | ALS2CR4 | Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4 | 3.87 | 2.59E‐03 |
| NM_004086.1 | COCH | Coagulation factor C homolog, cochlin (Limulus polyphemus) | 3.82 | 2.86E‐03 |
| NM_005899.3 | NBR1 | Neighbor of BRCA1 gene 1 | 3.78 | 3.05E‐03 |
| NM_001077445.1 | PHF16 | PHD finger protein 16 | 3.70 | 3.48E‐03 |
| NM_018330.3 | KIAA1598 | KIAA1598 | 3.61 | 4.12E‐03 |
| NM_003656.3 | CAMK1 | Calcium/calmodulin‐dependent protein kinase I | 3.59 | 4.26E‐03 |
| NM_018950.1 | HLA‐F | Major histocompatibility complex, class I, F | 3.58 | 4.29E‐03 |
| NM_145177.1 | DHRSX | Dehydrogenase/reductase (SDR family) X‐linked | 3.57 | 4.38E‐03 |
t‐values and P‐values were indicated with an individual two‐sample t‐test. E‐05, E‐04 and E‐03 represent 10−5, 10−4 and 10−3, respectively. NCBI Acc. No., National Center for Biotechnology Information accession number; OGS, official gene symbol.