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Relationship between the Met‐enkephalin (MENK) levels and infiltration of T lymphocytes in subcutaneous tumors
| MENK (ng/g) | T lymphocytes (per mm2) | ||
|---|---|---|---|
| CT26 | |||
| None | 95 ± 16 | 18 ± 6 | |
| MENK antibody † | 17 ± 10 | 96 ± 23 | P < 0.0001 |
| IEC6A | |||
| None | 36 ± 9 | 78 ± 20 | |
| MENK anitbody † | 12 ± 6 | 104 ± 29 | P = 0.0388 |
| MENK injection † | 74 ± 15 | 24 ± 10 | P = 0.0002 |
Anti‐MENK antibody (20 µg/mouse) or MENK (12 µg/mouse) were injected into the tumors at 24 h before death.
