Figure 5.

Effects of 5‐fluorouracil (5FU), cisplatin and etoposide on the expression levels of dynamin 2, coxsackie virus and adenovirus receptor (CAR) andβ3‐integrin. (A) Dynamin 2 mRNA was quantified by real‐time reverse transcription polymerase chain reaction from total RNA extracted from SUIT‐2 cells treated with 5FU, cisplatin or etoposide at 4, 8, 12, 24 and 48 h after treatment and expressed as the fold increases relative to untreated cells. (B) CAR mRNA was quantified and expressed as described in (a). (C) β3‐integrin mRNA was quantified and expressed as described in (A). Each value represents the mean ± SD of triplicate measurements. **P < 0.01. *P < 0.05, compared with 0 h cells.