Table 4.
Genes of cluster 3
| Category | Gene name | GenBank accession number | Expression ratio | ||
|---|---|---|---|---|---|
| CON | NC | CA | |||
| Cell surface antigens | MHC class II antigen RT1.B‐1 β‐chain | X56596 | 0.85 | 0.49 | 1.44 |
| Transcription factors | Hepatic nuclear factor 4 | D10554 | 1.09 | 0.60 | 1.56 |
| Mini chromosome maintenance deficient 6 | U17565 | 1.04 | 0.71 | 1.46 | |
| Leukemia/lymphoma related factor | D88450 | 0.62 | 0.83 | 8.57 | |
| Trafficking/targeting proteins | Clathrin, heavy polypeptide | J03583 | 1.25 | 0.60 | 1.58 |
| Metabolism‐related factors | Peroxiredoxin 6 | AF110732 | 1.23 | 0.68 | 1.79 |
| Superoxide dismutase 3 | Z24721 | 1.19 | 0.67 | 1.16 | |
| Glutamate dehydrogenase | X14044 | 0.95 | 0.82 | 1.51 | |
| Prostaglandin‐endoperoxide synthase 1/cyclo‐oxygenase 1 | NM017043 | 0.73 | 0.63 | 1.12 | |
| Dimethylglycine dehydrogenase precursor | X55995 | 1.01 | 0.49 | 1.72 | |
| Hydroxyacid oxidase 3/glycolate oxidase 3 | X67156 | 1.33 | 0.68 | 1.14 | |
| Glycerol‐3‐phosphate dehydrogenase 2 | X78593 | 1.27 | 0.45 | 1.55 | |
| β‐4N‐acetylgalactosaminyltransferase | D17809 | 0.57 | 0.53 | 1.44 | |
| Post‐translational modification/ protein folding‐related factors | Peptidylglycine α‐amidating monooxygenase | M25732 | 0.55 | 1.14 | 4.71 |
| Translation | Eukaryotic translation initiation factor 2B, subunit 2 | U31880 | 0.91 | 0.78 | 1.48 |
| RNA processing/turnover/ transport‐related factors | Cyclin L | AF030091 | 0.75 | 0.75 | 1.71 |
| DNA binding and chromatin proteins | Histone H10 | U49737 | 1.25 | 0.68 | 1.11 |
| Cell signaling/extracellular communicating factors | Endothelin‐2 | U64949 | 1.03 | 0.55 | 1.17 |
| Intracellular transducers/ effectors/modulators | Insulin receptor substrate 3 | U93880 | 0.95 | 0.91 | 1.35 |
| PCTAIRE3 | AB005541 | 0.81 | 0.37 | 2.07 | |
| Calbindin 1 | M31178 | 0.79 | 0.75 | 1.85 | |
| Arrestin, β1 | M91589 | 0.90 | 0.93 | 1.55 | |
| Adenylyl cyclase 2 | M80550 | 0.83 | 0.68 | 1.34 | |
| Homeodomain‐interacting protein kinase 3 | AF036959 | 0.93 | 0.66 | 1.65 | |
| Tuberous sclerosis 2 | U24150 | 1.04 | 0.75 | 1.66 | |
| AMP‐activated protein kinase | Z29486 | 1.35 | 0.74 | 1.49 | |
| Sialyltransferase 5 | X76988 | 1.02 | 0.62 | 1.46 | |
| Thyroid hormone receptor interactor 10 | AB006914 | 0.58 | 0.67 | 1.81 | |
| Peroxiredoxin 5 | Y17295 | 1.02 | 0.87 | 1.47 | |
| Sialyltransferase 8 | U55938 | 1.10 | 0.68 | 2.16 | |
| Cytoskeleton/motility proteins | Kinesin heavy chain member 2 | AF155824 | 0.91 | 0.76 | 1.21 |
| Others | Cell growth regulatory with EF‐hand domain | U66470 | 1.36 | 0.61 | 1.33 |
| Homeobox protein R3 | M37567 | 1.01 | 0.55 | 2.28 | |
| ADAMTS‐1/METH‐1 | AF149118 | 0.94 | 0.67 | 1.29 | |
| Outer mitochondrial membrane receptor rTOM20 | U21871 | 1.01 | 0.94 | 1.92 | |
| Coronin, actin‐binding protein, 1B | AJ006064 | 1.41 | 0.53 | 1.40 | |
| Unconventional myosin Myr2 I heavy chain | X74800 | 0.98 | 0.86 | 1.41 | |
| Replication factor C 2 | AF208499 | 0.81 | 0.76 | 1.26 | |
| Solute carrier family 29, member 1/ENT1 | AF015304 | 0.94 | 0.55 | 1.47 | |
| Aspartyl‐tRNA synthetase/DRS1 | U30812 | 1.16 | 0.50 | 1.16 | |
| Quinoid dihydropteridine reductase | J03481 | 1.18 | 0.40 | 1.44 | |
| Fibrinogen, γ‐polypeptide | J00734 | 0.63 | 0.48 | 5.35 | |
| Myosin light chain kinase 2 | J03886 | 0.98 | 0.46 | 1.51 | |
| Hyperpolarization‐activated cyclin nucleotide‐gated cation channel 1 | AF247450 | 1.00 | 0.27 | 1.20 | |
| ECL | X56190 | 0.79 | 0.50 | 1.57 | |
CON, normal liver; NC, surrounding non‐cancerous liver; CA, HCC sample.