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. 2010 May 12;101(8):1913–1919. doi: 10.1111/j.1349-7006.2010.01614.x

Table 3.

 Univariate and multivariate Cox regression analysis of potential prognostic factors for DFS

Variable Univariate analysis Multivariate analysis
Number Median survival (months) P‐value HR 95% CI P‐value
UICC stage
 I, II 29 21.6 0.1003
 III, IV 10 9.9
Tumor size (cm)
 <4 18 18.9 0.0649 2.048 0.862–5.077 0.1218
 ≥4 21 10.9
Histologic differentiation
 Well–Mod. 30 18.1 0.8534
 Poor 9 19.8
Lymph node metastasis
 + 12 9.7 0.0219 2.44 0.335–2.213 0.0269
  − 27 29.8
CD68
 High 19 16.3 0.0623
 Low 20 18.3
CD163
 High 20 11.2 0.0369 2.48 1.031–5.983 0.0426
 Low 19 23.7
FOXP3
 High 20 10.4 0.0999 1.003 0.244–4.129 0.9964
 Low 19 20.3

CI, confidence interval; DFS, disease free survival; FOXP3, forkhead box P3; HR, hazard ratio; UICC, International Union Against Cancer.

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