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Analysis of five tumors with double mutations of the epidermal growth factor receptor gene
| Sample | 5′ mutation | 3′ mutation | No. colonies | Same allele | |
|---|---|---|---|---|---|
| Total | 5′ Mt/3′ Mt | ||||
| KD641 | G719S | S768I | 52 | 16 (31%) | Yes |
| KD826 | G719C | S768I | 40 | 38 (95%) | Yes |
| KD530 | S768I | V769L | 26 | 14 (54%) | Yes |
| KD514 | E709A | L858R | 28 | 14 (50%) | Yes |
| KD921 | E709G | L858R | 36 | 16 (44%) | Yes |
Mt, mutation.
