Table 2.

Incidences and multiplicities of microscopic tumors of the tongue and esophagus

	Allele	Tongue †			Esophagus
		Dysplasia	Papilloma	SCC	Dysplasia	Papilloma	SCC
Incidence	chip/+	91.3	17.4	60.9	100.0	13.0	82.6
(%)	chip/c	81.0	4.8	19.0*	71.4**	19.0	42.9**
Multiplicity	chip/+	1.61 ± 0.99	0.17 ± 0.39	0.91 ± 0.85	2.26 ± 1.66	0.14 ± 0.34	1.30 ± 1.22
(Mean ± SD)	chip/c	1.52 ± 1.21	0.05 ± 0.22	0.19 ± 0.40**	1.48 ± 1.47	0.19 ± 0.40	0.48 ± 0.60***

^* Significantly different from chip/+ (P < 0.005).

^** Significantly different from chip/+ (P < 0.01).

^*** Significantly different from chip/+ (P < 0.05).

^† Incidences and multiplicities of microscopic tumors in the tongue were determined on the histological sections at the longitudinal center of the tongue.

chip/+, control mice; chip/c, hypomethylated mice.