Table 1.

Relationship between runt‐related transcription factor‐3 (RUNX3) expression and clinicopathological parameters in 73 adenoid cystic carcinomas

Variables	Number of cases	RUNX3 expression †			P‐values**
		Low	Intermediate	High
Cases	73	18	37	18
Age at diagnosis
<46 years	36	6	20	10
≥46 years	37	12	17	8	0.293
Gender
Female	43	9	19	15
Male	30	9	18	3	0.052
Tumor site
Major salivary gland	29	10	14	5
Minor salivary gland	44	8	23	13	0.222
T‐phage
T1‐3	31	4	16	11
T4	42	14	21	7	0.061
Histotypes
Cribriform	32	3	17	12
Tubular	16	4	9	3
Solid	25	11	11	3	0.025*
Distant metastasis
+	7	5	2	0
–	66	13	35	18	0.009*
Perineural invasion
+	41	11	19	11
–	32	7	18	7	0.703
Lymph node involvement
N+	8	4	3	1
N0	65	14	34	17	0.203

^* Statistically significant;

^** χ²‐test;

^† tertile cut‐off: low ≤ 6.94%, 6.94% < Intermediate < 14.91%, High ≥ 14.91%.