Survival curves of mice generated by (a) BA
tg/– × Bcl11b
+/– and (b) BA
tg/– × H2AX
+/–. The survival curves of BA
−/–
Bcl11b
+/+ and BA
−/–
HX2A
+/+, BA
tg/–
Bcl11b
+/+ and BA
tg/–
H2AX
+/+, BA
−/–
Bcl11b
+/– and BA
−/–
H2AX
+/–, and BA
tg/–
Bcl11b
+/– and BA
tg/–
H2AX
+/– mice are shown as thin dotted, thick dotted, thin continuous, and thick continuous lines respectively. In the BA
tg/– × Bcl11b
+/– group, 8 of 15 BA
tg/–
Bcl11b
+/– mice died within 7 months of age and in the BA
tg/– × H2AX
+/– group, 4 of 11 BA
tg/–
H2AXb
+/– died within 3 months of age. The number of an unanalyzable BA
tg/–
Bcl11b
+/– mouse due to death (no. 3) is shown in parentheses.