Table 1.

List of peptides that differed between normal and cancerous tongue epithelia

ID	M/Z	RT	Charge	Accession number	Protein description	Mascot score	Peptide sequence	Normal (mean ± SD)	Cancer (mean ± SD)	P‐values*
4818	509.3	49.2	2	gi|62897663	Keratin 13 isoform a variant	73.89	VLDELTLSK	6088 ± 2506	491 ± 149	2.56E‐04
13 827	703.9	55.6	2	gi|109255249	Keratin 4	59.37	VDSLNDEINFLK	1078 ± 633	23 ± 4	8.76E‐04
7777	572.9	44.2	2	gi|62897663	Keratin 13 isoform a variant	54.31	ILTATIENNR	4338 ± 1645	233 ± 82	1.09E‐04
673	418.2	47.6	2	gi|62897663	Keratin 13 isoform a variant	53.6	LAVDDFR	9241 ± 3859	848 ± 474	2.51E‐04
4572	504.3	46.2	2	gi|62897663	Keratin 13 isoform a variant	47.73	YENELALR	5147 ± 2130	303 ± 95	1.77E‐04
6588	546.8	51.8	2	gi|80478896	Transglutaminase 3 (E polypeptide, protein‐ glutamine‐gamma‐ glutamyltransferase)	42.36	FSSQELILR	209 ± 103	21 ± 15	6.36E‐04
20 149	870.4	48.0	2	gi|442631	Chain, annexin I	41.86	SEDFGVNEDLADSDAR	141 ± 51	32 ± 19	5.41E‐04
1203	431.3	43.5	2	gi|119568898	hCG1643722, isoform CRA_b	41.57	VMLTELR	9947 ± 4751	561 ± 163	4.78E‐04
5504	521.8	48.7	2	gi|62897663	Keratin 13 isoform a variant	38.65	VILEIDNAR	9570 ± 2752	890 ± 302	3.04E‐05
12 366	673.4	55.1	2	gi|11360071	Hypothetical protein DKFZp434K0115.1 – human (fragment)	38.49	KTLEEQISEIR	1757 ± 615	73 ± 9	3.40E‐05
434	412.3	42.9	2	gi|6016414	Keratin, type I cuticular Ha2 (hair keratin, type I Ha2) (keratin‐32)	38.38	LASYLTR	5312 ± 2562	359 ± 91	5.88E‐04

^† Paired t‐test.