Table 2.
Correlation between clinical characteristics of TSCC and TGM3 protein expression
| Characteristics | Total | Number of TGM3‐positive cases (%) | Number of TGM3‐negative cases (%) | P‐values* |
|---|---|---|---|---|
| Total | 53 | 12 (22.6) | 41 (77.4) | |
| Age (years) | ||||
| ≤60 | 27 | 9 (33.3) | 18 (66.7) | 0.0994 |
| >60 | 26 | 3 (11.5) | 23 (88.5) | |
| Gender | ||||
| Male | 36 | 8 (22.2) | 28 (77.8) | 1.0000 |
| Female | 17 | 4 (23.5) | 13 (75.5) | |
| Stage | ||||
| I and II | 42 | 10 (23.8) | 32 (76.2) | 0.4705 |
| III and IV | 11 | 2 (18.2) | 9 (81.8) | |
| TNM classification | ||||
| T category | ||||
| T1 and T2 | 48 | 12 (25.0) | 36 (75.0) | 0.5765 |
| T3 and T4 | 5 | 0 (0) | 5 (100) | |
| N category | ||||
| N0 | 43 | 12 (27.9) | 31 (72.1) | 0.0932 |
| N1‐3 | 10 | 0 (0) | 10 (100) | |
| Histological grade | ||||
| Well | 22 | 9 (40.9) | 13 (59.1) | 0.0171 |
| Moderate or poor | 31 | 3 (9.7) | 28 (90.3) | |
*
P‐values were calculated by Fisher's exact test and considered statistically significant at <0.05 (two‐sided). TGM3, transglutaminase 3; TSCC, tongue squamous cell carcinoma.