Table 1.
Clinicopathologic parameters of esophageal squamous cell carcinoma (ESCC) patients and the correlation with p53 gene mutation in ESCC samples
| Characteristic | Patients | P | P53 gene mutation (N = 75) | P | |
|---|---|---|---|---|---|
| Total N = 75 (%) | Positive N = 34 (%) | Negative N = 41 (%) | |||
| Gender | P = 0.121 | ||||
| Male | 71 (94.7) | 34 (100) | 37 (90.2) | ||
| Female | 4 (5.3) | 0 | 4 (9.8) | ||
| Stage | P = 0.959 | ||||
| I | 6 (8.0) | 2 (5.9) | 4 (9.8) | ||
| IIA | 23 (30.7) | 10 (29.4) | 13 (31.7) | ||
| IIB | 17 (22.7) | 8 (23.5) | 9 (22.0) | ||
| III | 27 (36.0) | 13 (38.2) | 14 (34.1) | ||
| IV | 2 (2.7) | 1 (2.9) | 1 (2.4) | ||
| Depth of invasion | P = 0.927 | ||||
| T1 | 8 (10.7) | 3 (8.8) | 5 (12.2) | ||
| T2 | 28 (37.3) | 13 (38.2) | 15 (36.6) | ||
| T3 | 37 (49.3) | 17 (50.0) | 20 (48.8) | ||
| T4 | 2 (2.7) | 1 (2.9) | 1 (2.4) | ||
| Node involvement | P = 0.585 | ||||
| Absence | 29 (38.7) | 12 (35.3) | 17 (41.5) | ||
| Presence | 46 (61.3) | 22 (64.7) | 24 (58.5) | ||
| Cigarette | P < 0.001 | P = 0.123 | |||
| Smoker | 63 (84.0) | 31 (91.2) | 32 (78.0) | ||
| Non‐smoker | 12 (16.0) | 3 (8.8) | 9 (22.0) | ||
| Alcohol | P = 0.004 | P = 0.512 | |||
| Drinker | 50 (66.7) | 24 (70.6) | 26 (63.4) | ||
| Non‐drinker | 25 (33.3) | 10 (29.4) | 15 (36.6) | ||
| Betel quid chewing | P = 0.908 | P = 0.007 | |||
| Chewer | 38 (50.7) | 23 (67.6) | 15 (36.6) | ||
| Non‐chewer | 37 (49.3) | 11 (32.4) | 26 (63.4) | ||