Table 2.
Clinical characteristics of the subjects with breast or ovarian cancer
| Variables | Breast cancer † | Ovarian cancer ‡ | |
|---|---|---|---|
| Number of subjects | 126 | 18 | |
| Sex | Female | 122 | 18 |
| Male | 4 | – | |
| Age at diagnosis | Female | 46.2 ± 12.1 | 50.2 ± 11.8 |
| Male | 64.5 ± 3.7 | – | |
| Tumor size (T) | Tis | 2 ¶ | – |
| T1 | 66 | 11 | |
| T2 | 49 | 1 | |
| T3 | 4 | 4 | |
| Missing data (No.) | 5 | 2 | |
| Nodal status (N) | Negative | 95 | 10 |
| Positive | 24 | 5 | |
| Missing data (No.) | 7 | 3 | |
| Stage | 0 | 2 | – |
| I | 71 | 9 (IA 4, IC 5) | |
| II | 38 | 1 (IIA 1) | |
| III | 4 | 4 (IIIB 1, IIIC 3) | |
| IV | 1 | 1 | |
| Missing data (No.) | 13 | 3 | |
| Histology | Non‐invasive | 2 | Serous 3, mucinous 3, |
| Invasive | 111 | endmetrioid 2, clear cell 2, | |
| Missing data (No.) | 13 | undifferentiated 2, mixed‐cell type 2, others 2, sex‐cord stromal tumor 1, germ cell tumor 1 | |
| Estrogen receptor status | Positive | 72 | |
| Negative | 37 | ||
| Missing data (No.) | 17 | ||
| Progesterone receptor status | Positive | 64 | |
| Negative | 44 | ||
| Missing data (No.) | 18 | ||
| Histological grade | Grade 1 | 24 | |
| Grade 2 | 37 | ||
| Grade 3 | 24 | ||
| Missing data (No.) | 41 | ||
| Laterality | Unilateral | 104 | |
| Bilateral | 22 | ||
| Mutational status | No mutation | 91 | 13 |
| BRCA1/2 | 35 | 5 | |
| BRCA1 | 16 | 5 | |
| BRCA2 | 19 | 0 |
†
Includes subjects with ovarian cancer (n = 9).
‡
Includes subjects with breast cancer (n = 9).
¶
¶Subjects with multiple primary breast cancer, in which histology of the first primary cancer was pTis. They were enrolled in the study as the histology of the second primary breast cancer was ascertained to be invasive cancer.