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Nobiletin inhibited endothelial cell (EC) proliferation. After a 72‐h culture in the presence of various concentrations of nobiletin, cell numbers of (A) human umbilical vein EC and (B) human dermal microvascular EC were determined with a Coulter counter. Values are expressed as means ± SE (n = 3). *P < 0.05, **P < 0.01, as compared with the control.
