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. 2009 Oct 12;101(2):321–327. doi: 10.1111/j.1349-7006.2009.01397.x

Figure 4.

Figure 4

 Correlation between hypermethylation and Ki‐67 expression. (a) Ki‐67 protein expression did not correlate significantly with the occurrence of adenomatous polyposis coli (APC) promoter methylation in atypical endometrial hyperplasia (AH) (P = 0.222). (b) Ki‐67 protein expression correlated significantly with the occurrence of APC promoter methylation in stage I and II endometrial carcinomas ECs (P = 0.006). The International Federation of Gynecology and Obstetrics (FIGO) staging system was applied. (c) No significant correlation was observed between Ki‐67 immunoexpression and APC promoter hypermethylation in advanced stage ECs, FIGO III and IV (P = 0.797). (d) No significant correlation was observed between Ki‐67 immunoexpression and epithelial cadherin (E‐cadherin) promoter hypermethylation in ECs (P = 0.437).