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. 2009 Oct 12;101(2):559–567. doi: 10.1111/j.1349-7006.2009.01396.x

Figure 6.

Figure 6

 Inhibition of tumor growth in SW1990 pancreatic tumor xenograft study. (a) Antitumor effect of adenovirus containing X chromosome‐linked inhibitor of apoptosis protein‐associated factor 1 construct, Ad5/F35‐XAF1 (XAF1), in nude mice implanted s.c. with SW1990 pancreatic cancer cells. *P < 0.05 versus UT (untreated); #P < 0.05 versus Vector (adenovirus alone). GEM, gemcitabine. (b) Scatter plot of tumor weight. Black bars, median weight for the tumors in each group (n = 5); triangle, tumor weight of a xenograft. (c) Immunohistochemical analysis of tumor sections from each treatment group, with antibodies against XAF1, the proliferation marker Proliferating Cell Nuclear Antigen (PCNA) and the apoptotic marker TUNEL.