Figure 5.
Numbers of methylated tumor suppressor genes (TSGs) in 45 germ cell tumors. The large and small horizontal bars indicate the mean number of methylated TSGs and the mean number ± standard deviation (SD), respectively. (A) The number of methylated TSGs was higher in yolk sac tumors than in seminomas (P < 0.001) or teratomas (P = 0.004) by Student's t‐test. (B, C) The number of methylated TSGs was lower in tumors in the normal reprogramming pathway than in tumors in the abnormal pathway (P = 0.042), and in tumors with the UU/UU epigenotype than in tumors with other epigenotypes (P = 0.048).