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Effect of branched‐chain amino acid (BCAA) supplementation on hepatic cell proliferation in diethylnitrosamine‐treated C57BL/KsJ‐db/db mice. (a) Immunohistochemical expression of proliferating cell nuclear antigen (PCNA) in the liver of basal diet (CRF‐1)‐fed, or casein‐ or BCAA‐supplemented treated mice. (b) PCNA‐labeling index in non‐lesional hepatocytes was determined by counting the PCNA‐positive nuclei in the hepatocytes. *P < 0.05; **P < 0.01.
