Skip to main content
. 2011 Feb 10;102(4):776–783. doi: 10.1111/j.1349-7006.2011.01848.x

Figure 4.

Figure 4

 (A) Vorinostat restored RUNX3 in a dose‐ and time‐dependent manner. The Mz‐Ch‐A2 and MiaPaca‐2 cells, RUNX3‐non expressing biliary tract and pancreatic cancer cell lines, respectively, were treated with 0–10 μM vorinostat for 24 and 48 h, total RNA was isolated, and cDNA was synthesized as described. RUNX3 mRNA was measured by real‐time PCR. The data are expressed as means ± SD of three independent experiments. (B) Immunohistochemical staining of RUNX3 in Mz‐Ch‐A2 cells treated with 0 or 10 μM vorinostat for 48 h.