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. 2011 Feb 10;102(4):776–783. doi: 10.1111/j.1349-7006.2011.01848.x

Figure 6.

Figure 6

 (A) Effect of RUNX3 siRNA on RUNX3 mRNA expression in Mz‐ChA‐2 cells by real‐time PCR. (B) Effect of RUNX3 siRNA on TGF‐β signaling in Mz‐ChA‐2 cells was assessed by a luciferase assay using the p3TP‐Lux reporter plasmid. (C) Effects of RUNX3 siRNA on TGF‐β1‐dependent p21mRNA expression was assessed by real‐time PCR. Cells were cultured with 5 μM vorinostat with or without 5 ng/mL TGF‐β1 for 48 h. The data are expressed as means ± SD of three independent experiments. *P < 0.05 when compared with the value derived by non‐RUNX3 siRNA stimulation.