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Morphology and growth curve of parental cells and human telomerase reverse transcriptase (hTERT)‐infected cells. (a) Cumulative growth curve in Hc3716 human fetal hepatocytes and Hc3716‐hTERT. (b) Morphology of Hc3716 [88 population doubling levels (PDL); senescent state] and Hc3716‐hTERT (112 PDL). (c) Cumulative growth curve in normal non‐parenchymal cells (NPC2) and NPC2‐hTERT. (d) Morphology of NPC2 (24 PDL; senescent state) and NPC2‐hTERT (28 PDL).
