Figure 4.
(a) mRNA expression of hepatocyte nuclear factor 4 (HNF4) and cytochrome P450 (CYP)/3A7 in normal human fetal hepatocytes (Hc3716) and those infected with human telomerase reverse transcriptase (Hc3716‐hTERT) were examined by RT‐PCR. C, confluent monolayers; P, proliferative phase. (b) Induction of CYP/3A4 and CYP/3A7 after treatment with nifedipine and rifampicin in Hc3716 and Hc3716‐hTERT was examined by RT‐PCR. GAPDH was used as an internal control. Control, no treatment.