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Table 2.

Phenotypes of the patients’ PBMC

Case Diagnosis Positive cells in PBMC (%) Positive cells in CD56+ cells (%)
CD3 CD4 CD8 CD56 CD94 NKB1 NKAT2
1 HEN disease 53 49 11 30 § 98  1  1
2 HEN disease 27 22  6 63 97  1  1
3 HEN disease 12  9  4 51 99  1  1
4 Borderline HEN 41 31 20 13 80  5 34
5 Borderline HEN 33 18 10 42 93  2  3
6 Borderline HEN 32 17  8  8 73 12 14
7 Simple responder 65 25 22 14 53 12 29
8 Simple responder SLE 64 38 20  6 56 11 14
9 Simple responder 76 46 27  5 43  7 17
10 Simple responder 51 35 22 12 46 20 21
11 Simple responder 55 38 22 11 54  8 27
8 healthy donors (mean ± SD) 62 ± 7.9 38 ± 8.2 23.3 ± 4.8 18.0 ± 5.8 49.8 ± 5.6 15.5 ± 5.3 25.6 ± 8.2

The underlined values are above the mean + 2 SD of the healthy donors.

The underlined numbers are below the mean − 2 SD of the healthy donors.

§

When the patient was 2–5 years old, the percentage was ∼60%. SLE, systemic lupus erythematosus.