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Table 3.

Responses observed in patients with relapsed or refractory B‐cell non‐Hodgkin's lymphoma (B‐NHL) after treatment with salvage chemoimmunotherapy incorporating cyclophosphamide, cytarabine, etoposide, dexamethasone, and rituximab

Type of B‐NHL Prior treatment Total no. CR or Cru Overall response
Indolent B‐NHL All n = 17 n = 16 n = 17
94% (71–99%) 100% (84–100%)
Previous rituximab n = 12 n = 11 n = 12
92% (62–99%) 100% (78–100%)
Rituximab‐naive n = 5 n = 5 n = 5
100% (55–100%) 100% (55–100%)
Aggressive B‐NHL All n = 15 n = 8 n = 10
53% (27–79%) 67% (38–88%)
Previous rituximab n = 8 n = 4 n = 5
50% (16–84%) 63% (24–91%)
Rituximab‐naive n = 7 n = 4 n = 5
57% (18–90%) 71% (29–96%)
Total All n = 32 n = 24 n = 27
75% (57–89%) 84% (67–95%)
Previous rituximab n = 20 n = 15 n = 17
75% (51–91%) 85% (62–97%)
Rituximab‐naive n = 12 n = 9 n = 10
75% (43–95%) 83% (52–98%)

Ranges in parentheses indicate 95% confidence interval. CR, complete response; CRu, complete response unconfirmed.