Figure 6.

5‐Fluorouracil (5‐FU) + interferon‐α (IFN‐α) + poly I:C most effectively induced cell death in various cancer cell lines. (a–e) Cancer cell lines harboring wild‐type p53 (a,b), mutant p53 (c), and normal cells (d,e) were untreated or treated with the indicated reagents. % LDH release was determined. Values are presented as mean ± SE from triplicate tests. *P < 0.05; **P < 0.01; ***P < 0.001 vs untreated group, determined by anova with Tukey–Kramer. Except for the indicated groups, the difference between other groups and control was not statistically significant.