Table 3.

Genotype distributions of the RUNX3 tSNPs in gastric cancer cases and controls and risk estimates

SNP no.	SNP ID	Genotype	Cases		Controls		P‐value*	Adjusted OR (95% CI) †
			n	%	n	%
1	rs6672420	TT	149	47.7	161	49.4	0.290	1.00 (ref.)
		TA	130	41.7	142	43.6		1.00 (0.72–1.39)
		AA	33	10.6	23	7.0		1.64 (0.91–2.93)
2	rs11249208	AA	162	51.9	175	53.9	0.874	1.00 (ref.)
		AG	133	42.6	134	41.2		1.08 (0.78–1.50)
		GG	17	5.5	16	4.9		1.21 (0.59–2.49)
3	rs11249206	TT	60	19.3	119	36.5	<0.001	1.00 (ref.)
		TC	212	68.2	162	49.7		2.61 (1.79–3.80)
		CC	39	12.5	45	13.8		1.75 (1.03–2.99)
4	rs7551188	TT	96	30.8	102	31.3	0.107	1.00 (ref.)
		CT	178	57.0	166	50.9		1.11 (0.78–1.58)
		CC	38	12.2	58	17.8		0.69 (0.42–1.13)
5	rs1395621	CC	104	33.3	115	35.0	0.491	1.00 (ref.)
		CT	154	49.4	148	45.0		1.13 (0.80–1.61)
		TT	54	17.3	66	20.0		0.92 (0.59–1.45)
6	rs906296	GG	175	56.1	171	52.6	0.520	1.00 (ref.)
		GC	118	37.8	137	42.2		0.85 (0.61–1.17)
		CC	19	6.1	17	5.2		1.06 (0.53–2.12)
7	rs760805	TT	47	15.1	67	20.4	0.022	1.00 (ref.)
		AT	151	48.4	173	52.6		1.21 (0.78–1.88)
		AA	114	36.5	89	27.0		1.82 (1.14–2.92)
8	rs2236852	AA	42	13.5	81	24.8	<0.001	1.00 (ref.)
		GA	187	59.9	146	44.8		2.49 (1.61–3.84)
		GG	83	26.6	99	30.4		1.69 (1.05–2.72)
9	rs9438876	AA	158	50.6	164	49.8	0.974	1.00 (ref.)
		AG	130	41.7	140	42.6		0.96 (0.69–1.33)
		GG	24	7.7	25	7.6		0.97 (0.53–1.78)
10	rs2282718	GG	115	36.8	129	39.6	0.388	1.00 (ref.)
		GA	155	49.7	145	44.5		1.20 (0.85–1.69)
		AA	42	13.5	52	15.9		0.89 (0.55–1.44)

^* Two‐sided χ² test for the frequency distribution.

^† Adjusted for age, sex, smoking status, and alcohol use.