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Association between WW‐domain‐containing oxidoreductase (Wwox) and mothers against decapentaplegic homolog 4 (Smad4) expression in pancreatic carcinoma (PC) cells. (a) Representative immunohistochemistry results for Wwox and Smad4. (b) Frequencies of loss of Smad4 expression in PC samples. (c) Wwox modulated Smad4 expression at the protein level in PANC‐1 cells. pWWOX was transfected into PANC‐1 cells and the cells were collected 48 after transfection.
