Table 1.

 International Germ Cell Cancer Consensus Group (IGCCCG) classification of metastatic germ cell cancers

	Non‐seminoma	Seminoma
Good prognosis	Testis/retroperitoneal primary	Any primary site
	No non‐pulmonary visceral metastasis	No non‐pulmonary visceral metastasis
	Good markers	Normal AFP, any hCG, any LDH
	5‐year PFS 89%, 5‐year OS 92%	5‐year PFS 82%, 5‐year OS 86%
Intermediate prognosis	Testis/retroperitoneal primary	Any primary site
	No non‐pulmonary visceral metastasis	Non‐pulmonary visceral metastasis
	Intermediate markers	Normal AFP, any hCG, any LDH
	5‐year PFS 75%, 5‐year OS 80%	5‐year PFS 67%, 5‐year OS 72%
Poor prognosis	Mediastinal primary or	No patient classified as poor‐prognosis
	Non‐pulmonary visceral metastasis
	Poor markers
	5‐year PFS 41%, 5‐year OS 48%

Marker criteria for non‐seminoma patients
	Good	Intermediate	Poor
AFP	<1000 ng/mL	>1000 ng/mL and <10 000 ng/mL	>10 000 ng/mL
hCG	<5000 IU/L	>5000 IU/L and <50 000 IU/L	>50 000 IU/L
LDH	<1.5× ULN	>1.5× ULN and <10× ULN	>10× ULN

AFP, α‐fetoprotein; hCG, human chorionic gonadotropin; LDH, lactate dehydrogenase; OS, overall survival; PFS, progression‐free survival; ULN, upper limit of normal.