Table 1.
Various cancer‐related databases
| Database name | Gene | Internet address | Ref |
|---|---|---|---|
| Locus‐specific Database | |||
| Familial Adenomatous Polyposis at GeneDis | APC | http://life2.tau.ac.il/GeneDis/Tables/APC/apc.html | |
| UMD Locus Specific Databases | APC, MEN1, VHL, others | http://www.umd.be/ | 4 |
| ATbase – a registry of patients with ataxia‐telangiectasia | ATM | http://www.cnt.ki.se/ATbase | |
| Ataxia‐Telangiectasia Mutation Database | ATM | http://www.benaroyaresearch.org/bri_investigators/atm.htm | |
| Bloom Syndrome‐BLMbase | BLM | http://bioinf.uta.fi/BLMbase/index2.html | 15 |
| Breast Cancer Mutation Database | BRCA1, BRCA2 | http://research.nhgri.nih.gov/bic/ | |
| CDKN2a Database Project (a human p16 database with annotation) | CDKN2A | http://biodesktop.uvm.edu/perl/p16 | |
| EGFR Mutation Database | EGFR | http://www.cityofhope.org/cmdl/egfr_db/index.html | |
| Fanconi Anaemia Mutation Database | FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, others | http://www.rockefeller.edu/fanconi/mutate/ | |
| LYSTbase: Mutation registry for Chediak‐Higashi syndrome | LYST | http://bioinf.uta.fi/LYSTbase/ | |
| MMR Databank | MLH1, MLH3, MSH2, MSH6, PMS1, PMS2 | http://www.insight‐group.org/ | |
| Mismatch Repair Genes Variant Database | MLH1, MSH6, MSH6 | http://www.med.mun.ca/mmrvariants/ | |
| NF1 International Mutation Databas | NF1 | http://www.nfmutation.org/ | |
| NF2 International Mutation Database | NF2 | http://www.nfmutation.org/ | |
| PTCH Mutation Database | PTCH | http://www.cybergene.se/cgi‐bin/w3‐msql/ptchbase/index.html | |
| Retinoblastoma Genetics | RB1 | http://www.verandi.de/joomla/ | 16 |
| SH2D1Abase: Mutation registry for X‐linked lymphopreliferative syndrome (XLP) | SH2D1A | http://bioinf.uta.fi/SH2D1Abase/ | |
| IARC TP53 Mutation Database | TP53 | http://www‐p53.iarc.fr/ | 3 |
| p53 web site | TP53 | http://p53.free.fr | |
| Database of Germline p53 Mutations | TP53 | http://www.lf2.cuni.cz/projects/germline_mut_p53.htm | 17 |
| p53 Mutation Database Analysis & Search | TP53 | http://p53.genome.ad.jp/ | |
| TP53 mutation database (UMD LSDB) | TP53 | http://www.umd.be:2072/ | 5 |
| Human p53 database and software | TP53 | http://sunsite.unc.edu/dnam/des_p53.htm | 18 |
| TSC Mutation Database | TSC1, TSC2 | http://chromium.liacs.nl/lovd/index.php?select_db=TSC1 | 19 |
| The Cardiff‐Rotterdam Tuberous sclerosis mutation database | TSC2 | http://www.uwcm.ac.uk/uwcm/mg/tsc_db/ | |
| WASbase: Mutation registry for Wiskott‐Aldrich syndrome (WAS) | WAS | http://bioinf.uta.fi/WASbase/ | |
| Database of WS‐associated WRN mutations | WRN | http://www.pathology.washington.edu/werner/ws_wrn.html | |
| GeneDis; Human Genetic Disease Database | http://life2.tau.ac.il/GeneDis/ | ||
| MutationView | 1 † | http://mutview.dmb.med.keio.ac.jp/ | 12,13 |
| Databases specialized for cancers | |||
| COSMIC; Catalogue of Somatic Mutations in Cancer | http://www.sanger.ac.uk/genetics/CGP/cosmic/ | 6 | |
| Atlas of Genetics and Cytogenetics in Oncology and Haematology | http://www.infobiogen.fr/services/chromcancer/ | 7 | |
| Cancer Genome Anatomy Project, CGAP | http://cgap.nci.nih.gov/ | 8 | |
| The Tumor Gene Database | http://condor.bcm.tmc.edu/ermb/tgdb/tgdb.html | 9 | |
| Cancer Gene Expression Database, CGED | http://cged.hgc.jp/ | 20 | |
| Central Mutation Databases | |||
| Genome Database, GDB | http://www.gdb.org/ | 21 | |
| Genatlas | http://www.dsi.univ‐paris5.fr/genatlas/ | 22 | |
| GeneCards Database | http://www.genecards.org/index.shtml | 23 | |
| Human Genome Variation database, HGVbase | http://hgvbase.cgb.ki.se/ | 24 | |
| Human Organised Whole Genome Database, HOWDY | http://howdy.jst.go.jp/ | 25 | |
| Online Mendelian Inheritance in Man, OMIM | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM | 10 | |
| Human Gene Mutation Database, HGMD | http://www.hgmd.cf.ac.uk/ac/index.php | 11 | |
| Sequence Tag Alignment and Consensus Knowledgebase, STACK | http://www.sanbi.ac.za/Dbases.html | 26 | |
†
1) See Table 2 and 4 for the genes included in MutationView/KMcancerDB.