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. 2007 Jul 25;98(10):1592–1596. doi: 10.1111/j.1349-7006.2007.00565.x

Figure 1.

Figure 1

The expression of insulin‐like growth factor binding protein 5 (IGFBP5) mRNA in normal breast tissues and breast cancers. The circles represented cases with negative IGFBP5 (‘–’), and the crosses represented cases with positive IGFBP5 (‘+’ to ‘+++’). The dash line represents the median in each group. IGFBP5 was negative in all of 30 normal breast tissues, but positive in 67% (10/15) of primary cancers with negative lymph nodes and in 93% (14/15) of primary cancers with positive nodes. (a) The expression difference of IGFBP5 mRNA in 30 breast cancers and paired normal breast tissues. (b) The mRNA level of IGFBP5 was higher in cases with positive lymph nodes (LN+) than cases with negative nodes (LN–).