Table 1.
Final body, alsolute and relative kidneys and liver weight of rats treated with Alz or Rub in a medium‐term multi‐organ carcinogenesis bioassay
| Control | 0.008% Alz | 0.04% Alz | 0.008% Rub | 0.04% Rub | |
|---|---|---|---|---|---|
| n‡ | 11 | 18 | 17 | 21 | 20 |
| Final BW (g) | 287.2 ± 21.4† | 287.1 ± 18.4 | 278.0 ± 16.7 | 279.0 ± 20.6 | 283.2 ± 17.8 |
| Kidneys | |||||
| Absolute (g) | 1.91 ± 0.27 | 1.99 ± 0.30 | 3.75 ± 6.53* | 1.98 ± 0.30 | 2.04 ± 0.32 |
| Relative (g/100 g BW) | 0.67 ± 0.09 | 0.69 ± 0.09 | 1.37 ± 2.42** | 0.71 ± 0.08 | 0.72 ± 0.11 |
| Liver | |||||
| Absolute (g) | 7.54 ± 0.91 | 7.32 ± 0.92 | 7.01 ± 0.69 | 7.08 ± 0.69 | 7.97 ± 0.98 |
| Relative (g/100 g BW) | 2.62 ± 0.22 | 2.54 ± 0.25 | 2.52 ± 0.14 | 2.54 ± 0.16 | 2.81 ± 0.23 |
*, **P < 0.05 and P < 0.01 versus controls, respectively. †Mean ± SD. ‡Effective number of animals. Alz, alizarin; BW, body weight; Rub, rubiadin.