Table 3.
Relationships between TTF‐1 expression and cell type classification system
| No. of cases (%) | Total | ||||
|---|---|---|---|---|---|
| TTF‐1 expression | |||||
| Negative | 1+ | 2+ | 3+ | ||
| Hobnail* | 1 (1) | 5 (5) | 8 (8) | 83 (86) | 97 |
| Mixed* | 5 (11) | 6 (13) | 9 (19) | 27 (57) | 47 |
| Columnar/cuboidal | 18 (46) | 4 (10) | 6 (15) | 11 (28) | 39 |
| Polygonal/oval | 8 (50) | 2 (13) | 2 (13) | 4 (25) | 16 |
| Goblet | 5 (83) | 0 | 1 (17) | 0 | 6 |
| Total | 37 (18) | 17 (8) | 26 (13) | 125 (61) | 205 |
For statistical analysis, thyroid transcription factor‐1 (TTF‐1) expression statuses were compiled into two groups, negative and 1+, and 2+ and 3+, and then frequencies of the statuses were compared among the subtypes by chi‐squared test or Fisher’s exact test. *vs each other type; P < 0.01, respectively.