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Relationships between p53, K‐ras, and EGFR mutations
| Genes | Mutations | No. of cases (%) | |||
|---|---|---|---|---|---|
| K‐ras mutations | p53 mutations | ||||
| + | − | + | − | ||
| EGFR | + | 1 (1) | 93 (99)* | 34 (36) | 60 (64)‡ |
| − | 17 (13) | 111 (87) | 62 (48) | 66 (52) | |
| p53 | + | 6 (6) | 90 (94) | ||
| − | 12 (10) | 114 (90) | |||
*P < 0.01 (by Fisher’s exact test). ‡P < 0.1 (by chi‐squared test). EGFR, epidermal growth factor receptor.
