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In situ hybridization of S100A2 (antisense probe) for adenocarcinomas. The cytoplasm of 30–40% of tumor cells of (a) bronchioloalveolar carcinomas (BAC) reacted positively against an antisense probe of S100A2, but those of (b) mixed BAC were negative. BAC, bronchioloalveolar carcinoma (types A and B); mixed BAC, adenocarcinoma mixed subtype with BAC component (type C).
