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. 2009 May 18;100(8):1434–1442. doi: 10.1111/j.1349-7006.2009.01219.x

Figure 3.

Figure 3

NTPDase2 expression increases the malignity of C6 gliomas in vivo. Representative HE sections of implanted (a,c) C6‐EYFP and (b,d) C6‐EYFP/NTPDase2 gliomas denote histological characteristics that define glioblastoma multiforme. Histological characteristics exhibited by C6‐EYFP/NTPDase2 gliomas indicate a dramatic increase in the malignant potential: extensive intratumoral hemorrhage (H), peripheric pseudopalisade (P), necrosis (N), peritumoral edema (PE), lymphocytic infiltration (LI), and vascular proliferation (V). The complete analysis is presented in Table 1. Scale bars = 100 µm (a,b); 50 µm (c,d).