Table 1.
Histology | C6 (n = 12) | C6‐EYFP (n = 6) | C6‐EYFP/NTPDase2 (n = 8) | C6‐EYFP/NTPDase2 Clopidogrel (n = 5) |
---|---|---|---|---|
Coagulative necrosis | 6/12 | 4/6 | 8/8 | 2/5 |
Intratumoral hemorrhage | 4/12 | 2/6 | 8/8 | 2/5 |
Lymphocytic infiltration | 10/12 | 6/6 | 8/8 | 4/5 |
Peritumoral edema | 5/12 | 2/6 | 8/8 | 2/5 |
Peripheral pseudopalisading | 5/12 | 3/6 | 6/8 | 1/5 |
Mitotic index: mitosis/ high power fields | 14.5 ± 5.0 | 16.6 ± 4.7 | 24.4 ± 3.0* | 8.0 ± 2.0*, † |
Significant difference between C6‐YN2 and control groups (C6 and C6‐Y),
significant difference between C6‐YN2 and C6‐YN2 clopidogrel‐treated group. P < 0.05 as determined by anova, followed by Tukey–Kramer test.