Table 1.

Histological characteristics of implanted gliomas

Histology	C6 (n = 12)	C6‐EYFP (n = 6)	C6‐EYFP/NTPDase2 (n = 8)	C6‐EYFP/NTPDase2 Clopidogrel (n = 5)
Coagulative necrosis	6/12	4/6	8/8	2/5
Intratumoral hemorrhage	4/12	2/6	8/8	2/5
Lymphocytic infiltration	10/12	6/6	8/8	4/5
Peritumoral edema	5/12	2/6	8/8	2/5
Peripheral pseudopalisading	5/12	3/6	6/8	1/5
Mitotic index: mitosis/ high power fields	14.5 ± 5.0	16.6 ± 4.7	24.4 ± 3.0*	8.0 ± 2.0*, †

^* Significant difference between C6‐YN2 and control groups (C6 and C6‐Y),

^† significant difference between C6‐YN2 and C6‐YN2 clopidogrel‐treated group. P < 0.05 as determined by anova, followed by Tukey–Kramer test.