Figure 1.

 Cell growth in vitro. As indicated, HepG2, Hep3B, and SK‐Hep‐1 cells were incubated with arsenic trioxide (ATO), genistein (GEN), ATO + GEN, or pretreated with N‐acetyl‐L‐cysteine (NAC) or butylated hydroxyanisole (BHA) followed by ATO + GEN, for 72 h. Untreated cells served as the control. Cell viability was determined using a Cell Counting Kit‐8 (CCK‐8) assay to calculate the growth index. *Significant reduction in the growth index from control; **highly significant difference at P < 0.001 from control; †significant reduction from same dose ATO treatment; ‡significant increase from 2 μm ATO + GEN treatment.