Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Roles of fragile histidine triad gene product (Fhit) in response to cellular stress. Depiction of replicative and oxidative stress pathways affected by Fhit expression. The lines between the nucleus and mitochondrion indicate that ROS produced in mitochondria influence the cell cycle and cause DNA damage, while nuclear DNA damage can lead to apoptosis pathways that involve the mitochondrial pathway.
