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Insulin‐like growth factor (IGF) increases radiosensitivity under hypoxic conditions though the phosphoinositide 3‐kinase–mammalian target of rapamycin pathway. The surviving fraction of (a) AsPC‐1, (b) Panc‐1, and (c) MCF‐7 cells in the conditions shown above each panel. IGF2, IGF‐II, 100 ng/mL; LY, LY294002, 10 µmol/L; Rap, rapamycin, 100 nmol/L. Experiments were repeated three times, and the mean ± SD are shown. *P < 0.05.
