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. 2009 Dec 19;101(4):984–990. doi: 10.1111/j.1349-7006.2009.01479.x

Figure 5.

Figure 5

 Microvessel densities of the FU‐MMT‐3 xenografts by CD31‐stainning (brown color). (a) The control group (no treatment) (×200). (b) Treatment with TNP‐470 alone (×200). (c) Treatment with TCP microspheres alone (×200). Basophilic TCP microspheres (arrow heads) were seen in tumor microvessel (×400) (inset in 5c). (d) Treatment with TNP‐470‐loaded TCP microspheres (×200). The mean microvessel densities (MVD) of all treatment groups were significantly lower compared to control. (e) The mean MVD in TNP‐470‐loaded TCP microspheres was significantly lower than those of the TNP‐470 treatment alone and TCP‐microsphere treatment alone.