Table 2.
Odds ratios (OR) and 95% confidence intervals (CI) for endometrial cancer according to frequency and quantitiy of alcohol intake
| Category | Cases (n = 148) | Controls (n = 1476) | Age‐adjusted OR (95% CI) | Multivariate OR (95% CI)† |
|---|---|---|---|---|
| Frequency of alcohol intake | ||||
| None | 108 | 929 | 1.00 (Reference) | 1.00 (Reference) |
| <1/week | 14 | 166 | 0.72 (0.40–1.29) | 0.71 (0.39–1.29) |
| 1–2/week | 11 | 119 | 0.79 (0.41–1.52) | 0.77 (0.40–1.50) |
| 3–4/week | 8 | 99 | 0.69 (0.33–1.46) | 0.67 (0.31–1.43) |
| 5‐/week | 7 | 154 | 0.39 (0.18–0.85) | 0.37 (0.17–0.82) |
| unknown | 0 | 9 | ||
| P‐trends | 0.011 | 0.009 | ||
| Amount of alcohol consumption | ||||
| None | 109 | 933 | 1.00 (Reference) | 1.00 (Reference) |
| <25 g/week | 23 | 246 | 0.79 (0.49–1.27) | 0.79 (0.49–1.28) |
| (median, range) (eta g/week) | (8.6, 2.9–24.2) | (8.6, 1.7–24.2) | ||
| 25–175 g/week | 12 | 232 | 0.44 (0.24–0.81) | 0.42 (0.23–0.79) |
| (median, range) (eta g/week) | (54.3, 25.9–96.6) | (69, 25.3–172.5) | ||
| >175 g/week | 3 | 47 | 0.54 (0.16–1.76) | 0.47 (0.14–1.58) |
| (median, range) (eta g/week) | (201.3, 179.4–552) | (276, 177.1–805) | ||
| unknown | 1 | 18 | ||
| P‐trends | 0.006 | 0.005 | ||
†
Multivariate models adjusted for age, smoking, body mass index, regular exercise, menstrual status, age at menarche, duration of menstruation, parity, diabetes history, hypertension history, contraceptive usage history, hormone replacement therapy, and flushing after drinking.