Table 4.
Impact of alcohol consumption according to self‐reported reaction to alcohol
| Category | Alcohol consumption | ||||
|---|---|---|---|---|---|
| None | <25 g/week | 25–175 g/week | >175 g/week | P‐trends | |
| Total (case/control) † | 109/933 | 23/246 | 12/232 | 3/47 | |
| Age‐adjusted OR (95% CI) | 1.00 (Reference) | 0.79 (0.49–1.27) | 0.44 (0.24–0.82) | 0.54 (0.16–1.76) | 0.006 |
| Multivariate OR (95% CI) | 1.00 (Reference) | 0.79 (0.49–1.28) | 0.42 (0.23–0.79) | 0.47 (0.14–1.58) | 0.005 |
| Flushing after drinking | |||||
| No (case/control) | 44/292 | 13/157 | 7/175 | 3/36 | |
| Age‐adjusted OR (95% CI) | 1.00 (Reference) | 0.51 (0.26–0.98) | 0.24 (0.11–0.56) | 0.49 (0.14–1.69) | 0.001 |
| Multivariate OR (95% CI) | 1.00 (Reference) | 0.53 (0.27–1.05) | 0.25 (0.11–0.59) | 0.48 (0.14–1.67) | 0.002 |
| Yes (case/control) | 61/574 | 9/86 | 5/55 | 0/10 | |
| Age‐adjusted OR (95% CI) | 1.00 (Reference) | 1.03 (0.49–2.15) | 0.89 (0.34–2.30) | NE | 0.560 |
| Multivariate OR (95% CI) ‡ | 1.00 (Reference) | 1.07 (0.51–2.27) | 0.97 (0.37–2.57) | NE | 0.677 |
| Unknown (case/control) | 4/67 | 1/3 | 0/2 | 0/1 | |
†
One case and 18 controls were excluded from analyzes due to lack of information on alcohol drinking.
‡
Multivariate models adjusted for age, smoking, body mass index, regular exercise, menstrual status, age at menarche, duration of menstruation, parity, diabetes history, hypertension history, contraceptive usage history, and hormone replacement therapy.
CI, confidence interval; NE, not estimated because of no case in this category; OR, odds ratio.