Table 6.
Summary of scoring of immunohistochemistry between Cluster IIa and IIb
| Total (n = 32) | Cluster IIa (n = 15) | Cluster IIb (n = 17) | P‐value | |
|---|---|---|---|---|
| p‐mTOR (Score 0 vs 1, 2) | 25 (78.1%) | 12 | 13 | 0.81 |
| p‐4EBP1 (Score 0 vs 1, 2) | 30 (93.8%) | 13 | 17 | 0.12 |
| p‐S6 (Score 0 vs 1, 2) | 14 (43.8%) | 4 | 10 | 0.067 |
| p‐ERK (Score 0 vs 1, 2) | 11 (34.3%) | 0 | 11 | <0.001 |
| sstr1, positive | 13 (40.6%) | 10 | 3 | 0.0048 |
| sstr2A, positive | 29 (90.6%) | 15 | 14 | 0.087 |
| sstr2B, positive | 7 (21.9%) | 4 | 3 | 0.54 |
| sstr3, positive | 12 (37.5%) | 8 | 4 | 0.082 |
| sstr5, positive | 25 (78.1%) | 15 | 10 | 0.0049 |
| p‐IGF‐1R, positive | 26 (81.3%) | 12 | 14 | 0.84 |
| Ki‐67 LI | ||||
| <2% | 20 (62.5%) | 5 | 15 | 0.0014 |
| ≥2% | 12 (37.5%) | 10 | 2 | |
4EBP1, eukaryotic initiation factor 4‐binding protein 1; ERK, extracellular signal‐regulated kinase; IGF‐1R, insulin‐like growth factor 1 receptor; LI, labeling index; mTOR, mammalian target of rapamycin; S6, ribosomal protein s6; sstr, somatostatin receptor. The bold values indicate the statistical significance.