. 2009 Jun 22;100(10):1794–1800. doi: 10.1111/j.1349-7006.2009.01250.x

Table 6.

Incidence and multiplicity of inducible nitric oxide synthase (iNOS)‐positive foci and intensity of tissue damage in inflamed thyroid capsular regions at week 4 in rats treated with sulfadimethoxine (SDM) with or without concomitant administration of aminoguanidine (AG) after N‐bis(2‐hydroxypropyl)nitrosamine (DHPN) initiation (N = 10)

		Group 1 DHPN–SDM + AG	Group 2 DHPN–SDM
iNOS‐positive foci	Incidence (%)	3 (30)	5 (50)
iNOS‐positive foci	Multiplicity (no./rat)	0.4 ± 0.7	0.6 ± 0.7
Single‐strand DNA‐positive cells	Incidence (%)	10 (100)	10 (100)
Single‐strand DNA‐positive cells	Multiplicity (no./rat)	24.3 ± 14.8	43.0 ± 32.4