Table 3.
Frequency of UGT1A7 haplotypes in healthy controls, hepatitis B virus (HBV) carriers, and patients with HBV‐related hepatocellular carcinoma (HCC) who participated in this study
| Haplotype (Ht; nucleotide at –341, –57, 33, 387, 391, 392, 622, and 756 locus) | Allele type | Controls No. (%) | HBV carriers No. (%) | HCC patients No. (%) |
|---|---|---|---|---|
| Ht1: CTCTCGTG | *1 | 368 (58.6) | 277 (62.1) | 262 (53.7) |
| Ht2: CGAGAACG | *3 | 156 (24.8) | 93 (20.9) | 121 (24.8) |
| Ht3: TTCGAATA | *2 | 71 (11.3) | 62 (13.9) | 78 (16.6) |
| Ht4: CTCGAATG | *2 | 14 (2.2) | 5 (1.1) | 12 (4.1) |
| Ht5: TGCGAATA | *2 | 10 (1.6) | 0 (0.0) | 1 (0.2) |
| Ht6: CGCTCGTG | *1 | 4 (0.6) | 1 (0.2) | 2 (0.4) |
| Ht7: CTCGAATA | *2 | 0 (0.0) | 3 (0.7) | 0 (0.0) |
| Ht8: CGCGAACG | *3 | 2 (0.3) | 0 (0.0) | 1 (0.2) |
| Ht9: CGAGAATG | *2 | 1 (0.2) | 2 (0.4) | 0 (0.0) |
| Ht10: CTCTCGTA | *1 | 0 (0.0) | 1 (0.2) | 0 (0.0) |
| Ht11: CGCGAATA | *2 | 2 (0.3) | 0 (0.0) | 0 (0.0) |
| Ht12: CGAGAACA | *3 | 0 (0.0) | 1 (0.2) | 0 (0.0) |
| Ht13: TTCTCGTA | *1 | 0 (0.0) | 1 (0.2) | 0 (0.0) |