Table 5.
Odds ratio (OR) and 95% confidence intervals (CI) of UGT1A7 allele type or haplotype (Ht) for hepatocellular carcinoma (HCC)
| Controls No. (%) | HBV carriers No. (%) | HCC patients No. (%) | OR 1† (95% CI) | P‐value | |
|---|---|---|---|---|---|
| Allele type | |||||
| *1/*1 | 107 (34.1) | 90 (40.4) | 69 (28.3) | 1.00 (reference) | |
| *1/*2 | 64 (20.4) | 43 (19.3) | 59 (24.2) | 1.79 (1.08–2.96) | 0.023 |
| *1/*3 | 94 (29.9) | 57 (25.6) | 67 (27.5) | 1.53 (0.96–2.46) | 0.076 |
| *2/*2 | 4 (1.2) | 6 (2.7) | 7 (2.9) | 1.52 (0.49–4.73) | 0.468 |
| *2/*3 | 26 (8.3) | 17 (7.6) | 29 (11.9) | 2.23 (1.13–4.37) | 0.020 |
| *3/*3 | 19 (6.1) | 10 (4.5) | 13 (5.3) | 1.70 (0.70–4.10) | 0.241 |
| Allele type | |||||
| *1/*1 | 107 (34.1) | 90 (40.4) | 69 (28.3) | 1.00 (reference) | |
| *1/others | 158 (50.3) | 100 (44.8) | 126 (51.6) | 1.64 (1.09–2.47) | 0.017 |
| Others/others | 49 (15.6) | 33 (14.8) | 49 (20.1) | 1.94 (1.13–3.33) | 0.017 |
| Ht1 | |||||
| Ht1/Ht1 | 106 (33.8) | 90 (40.4) | 69 (28.3) | 1.00 (reference) | |
| Ht1/others | 156 (49.7) | 97 (43.5) | 124 (50.8) | 1.67 (1.11–2.52) | 0.015 |
| Others/others | 52 (16.6) | 36 (16.1) | 51 (20.9) | 1.85 (1.09–3.14) | 0.023 |
1†
HCC patients versus hepatitis B virus (HBV) carriers.